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Overview:We are a synthetic organic chemistry group that focuses on designing, synthesizing, and studying complex molecules that address real-world problems in medicine and materials science. Projects in the lab range from fundamental synthetic methodology and mechanism studies through to target-directed complex molecule synthesis, medicinal chemistry and chemical biology studies, synthesis of functional polymers, and creation of new polymer crosslinkers — as well as advanced biological and mechanical studies that are used to characterize the molecules that we and others produce. The breadth of our research interests allows us to collaborate with a diverse array of researchers in other fields: from cell biologists and animal researchers through to protein crystallographers, computational chemists, mechanical engineers, and ballistics experts. Diversity of backgrounds, opinions, and areas of expertise is the foundation upon which the success of our lab is built. We recognize and embrace diversity in many forms, and strive to create an environment in which researchers from all different cultures, ethnicities, nationalities, religions, sexes, sexual orientations, genders, gender identities, socioeconomic status, age, physical abilities, marital and family status will feel an equal and valued part of our dynamic team. Our goal is to maintain a culture of inclusivity by encouraging, respecting, and engaging diverse perspectives and debate, in order to better our science and our scientific community. |
Contact:Jeremy E. Wulff
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Representative Publications From Our Principal Research Areas: |
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• Universal Crosslinkers: Science 2019 | • Structural Characterization: Nature 2019 | • Study of Biological Mechanism: ACS MedChemLett 2019 |
• Reaction Discovery: ChemComm 2019 | • Drug Delivery: Animals 2020 | • Functional Polymers: ACS Applied Polymer Materials 2019 |
• Total Synthesis: Tetrahedron 2015 | • Synthetic Methodology: J.Org.Chem. 2015 | • Structure-Based Drug Design: Org Lett 2012 |
Group News: |
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08/11/23: | We have a opening for one or two new postdocs – details here. |
25/05/23: | Bi's cleavable crosslinker paper appears in Angewandte Chemie – a long time coming! |
17/05/23: | A really cool collaboration with Yiqiang Zhan's group on the use of crosslinkers in perovskite solar cells appears in Joule. |
26/04/23: | A commentary from Mathieu & Jeremy appears in Nature. |
08/02/23: | Ben's paper on 2nd-gen functionalized polydicyclopentadiene appears in Macromolecules – congratulations Ben! |
18/11/22: | We are incredibly proud to announce Julia Levy as a recipient of a 2023 Rhodes Scholarship. |
10/11/22: | Jon Sader wins a second poster prize at our Department's Graduate Student Research Day. |
05/11/22: | A collaboration with the Akbari group appears in the Journal of Drug Delivery Science and Technology. |
23/08/22: | Stefania, Grace, and Fatima get a lovely journal cover to accompany their most recent publication. |
24/03/22: | A collaboration with Kevin Golovin's group is accepted for publication to the Chemical Engineering Journal. |
21/02/22: | Rashid & colleagues publish an innnovative diazirine-based primer in ACS Applied Polymer Materials. |
10/11/21: | Bi wins a presentation award at the UVic Chemistry Department's Graduate Student Research Day. |
10/11/21: | Bi is awarded the prestigious Nora & Mark Degoutiere Memorial Scholarship – congratulations! |
01/09/21: | Jon and Bryce publish a nice methodology paper in OBC. Go vinyl ethers! |
01/09/21: | A four-lab collaboration on making anti-viral fabrics appears in Scientific Reports. Congratualtions to all involved. |
01/09/21: | Jae and Huyen return to the group for their undergraduate thesis projects, and are joined by Ryu and Sarah. Welcome everyone! |
10/08/21: | Our huge diazirine structure–function study appears in Chemical Science. |
17/02/21: | Austin is recognized for the top MSc oral presentation at the Graduate Student Research Day. |
01/02/21: | Our paper on 2nd-generation crosslinkers appears in Chemical Science. |
15/01/21: | Huyen, Jae and Hamish join to work on undergraduate research projects – welcome to all! |
15/12/20: | Tong successfully defends her thesis – congratulations Dr. Li! |
11/12/20: | Tong publishes a paper on functionalized PDCPD copolymers in ACS Applied Polymer Materials. |
10/12/20: | James and our collaborators at Chinook Contract Research publish a great story in Animals on lidocaine-loaded castration bands. |
03/12/20: | Jon receives the 2020 Gerry Poulton award for excellence in Organic Chemistry. Well deserved! |
30/11/20: | Dr. Wulff is announced as the 2020 recipient of the UVic Faculty of Science Research Award. |
10/11/20: | Bi collects a well-earned poster presentation prized at the Graduate Student Research Day. Nice! |
01/11/20: | Rashid joins the group to work on various applications of crosslinker technology. |
01/09/20: | Ben joins the group to continue the polydicyclopentadiene legacy. |
05/08/20: | Tong, Hannah, Tyler and Chang describe some nice surface science on our functionalized polydicyclopentadiene material, in the open access journal Materials Advances. |
24/04/20: | A collaborative study with the Contstabel lab appears in The Plant Journal. |
20/11/19: | Stories on our new universal crosslinker appear in C&E News, Phys.Org and the UK Daily Mail. |
15/11/19: | We describe a universal polymer crosslinker in Science. |
12/11/19: | Tong Li wins the prize for best PhD talk at the department's Graduate Student Research Day. Great work Tong! |
24/08/19: | Profs. Wulff and Rosenberg run the Hood to Coast Relay in Oregon. |
15/08/19: | 2nd annual Wulff group beach day – photos here! |
15/08/19: | Tong and Tyler publish a weighty study of fPDCPD synthesis and properties in ACS Applied Polymer Materials. |
05/07/19: | Derek – together with former group members Ronan and Trevor, as well as several collaborators – publishes a nice story on PD1 drugs in ACS MedChemLett. |