Complete List of Papers and Patents: |
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#101. | M. L. Lepage, S. F. Musolino and J. E. Wulff (2024) Design, Exploitation, and Rational Improvements of Diazirine-Based Universal Polymer Crosslinkers. Accounts of Chemical Research, in press. (link). | |
#100. | Z. Fu, S. F. Musolino, W. Qing, H. Li, F. J. de Zwart, Z. Zheng, M. Cai, Y. Gao, B. de Bruin, X. Dai, J. E. Wulff and H. Zhang (2024) Direct Photopatterning of Colloidal Quantum Dots with Electronically Optimized Diazirine Reagents. Journal of the Americal Chemical Society, 146, 28895–28905. (link) | |
#99. | L. Michelini, T. Slaney, L. Qie, K. Corejova, M. L. Lepage, S. F. Musolino, D. Hong, G. A. DiLabio and J. E. Wulff (2024) A Diazirine’s Central Carbon is sp2-Hybridized, Facilitating Conjugation to Dye Molecules. ChemRxiv DOI:10.26434/chemrxiv-2024-bqp13. (link) | |
#98. | A. L. Burman, J. K. Sader and J. E. Wulff (2024) Structural Determination of a Carbocation-Derived Rearrangement Product Observed During Thiele Cage Opening: Insight Into the Mechanism of an Alkyl-Extended Pinacol Reaction. Canadian Journal of Chemistry, 102, 629–640. (link) | |
#97. | P. Kandanarachchi, G. A. Meyer, S. F. Musolino, J. E. Wulff and L. F. Rhodes (2024) Crosslinking Vinyl-Addition Polynorbornenes via Difunctional Diazirines to Generate Low Dielectric-Constant and Low Dielectric-Loss Thermosets. Macromolecular Rapid Communications, 45, 2400200. (link) | |
#96. | S. B. Reinecke, V. Yeddu, D. Zhang, C. Barr, J. E. Wulff, S. V. Dayneko, M. R. Kokaba and M. I. Saidaminov (2024) Multiple Stabilization Effects of Benzylhydrazine on Scalable Perovskite Precursor Inks for Improved Perovskite Solar Cell Production. Angewandte Chemie International Edition, 63, e202405422. (link) | |
#95. | F. J. de Zwart, L. A. Wolzak, K. J. van den Berg, M. J. Baran, J. E. Wulff, J. Flapper, and B. de Bruin (2024) Diazirine-Functionalized Polyurethane Crosslinkers for Isocyanate-Free Curing of Polyol-Based Coatings. ACS Applied Polymer Materials, 6, 3517–3522. (link) | |
#94. | R. Nazir, S. F. Musolino, M. A. MacFarlane and J. E. Wulff (2024) Surface Modification and Dyeing of Ultra-high-molecular-weight Polyethylene Fabrics using Diazirine-Based Polymers. ACS Applied Polymer Materials, 6, 1688–1697. (link) | |
#93. | J. Li, L. Bi, S. F. Musolino, J. E. Wulff and K. N. Sask (2024) Functionalization of Polydimethylsiloxane with Diazirine-Based Linkers for Covalent Protein Immobilization. ACS Applied Materials and Interfaces, 16, 1–16. (link) | |
#92. | M. Baran, R. Hof, A. Groot, I. Eurlings, J. Gijsbrechts, B. de Jong and J. E. Wulff (2024) Safety Evaluation of a Prototypical Diazirine-Based Covalent Crosslinker and Molecular Adhesive. International Journal of Toxicology, 43, 146–156 (link). ChemRXiv Preprint, DOI: 10.26434/chemrxiv-2023-02szg (link) | |
#91. | M. L. Lepage and J. E.. Wulff (2023) Mixed Plastics Upcycled Dynamically. Nature, 616, 663–664. (link) | |
#90. | L. Bi, B. Godwin, M. J. Baran, R. Nazir and J. E. Wulff (2023) A Cleavable Crosslinking Strategy for Commodity Polymer Functionalization and Generation of Reprocessable Thermosets. Angewandte Chemie International Edition, e202304708. (link) | |
#89. | K. Liu, S. Rafique, S. F. Musolino, F. Liu, Z. Cai, X. Li, Y. Yuan, Q. Bao, Y. Yang, J. Chu, X. Peng, C. Nie, W. Yuan, S. Zhang, J. Wang, Y. Pan, H. Zhang, X. Cai, Z. Shi, C. Li, H. Wang, L. Deng, T. Hu, Y. Wang, Y. Wang, S. Chen, L. Shi, P. Ayala, L. Yang, R. Che, J. E. Wulff, A. Yu and Y. Zhan (2023) Covalent Bonding Strategy to Enable Non-Volatile Organic Cation Perovskite for Highly Stable and Efficient Solar Cells. Joule, 7, 1033–1050. (link) | |
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#88. | M.-H. Tran, I. Booth, A. Azarakhshi, P. Berrang, J. Wulff and A. G. Brolo (2023) Synthesis of Graphene and Graphene Films with Minimal Structural Defects. ACS Omega, 8, 40387–40395. (link) | |
#87. | M. Mahbod, S. F. Musolino, J. E. Wulff, R. Vaziri and A. S. Milani (2023) Mechanical Characterization of Neat and Chemically Crosslinked UHMWPE Fabrics Subjected to Quasi-Static Loadings. Twenty-Third International Conference on Composite Materials (ICCM23). (link) | |
#86. | J. Wulff and B. Godwin (2023) Bi-functionalized Dicyclopentadiene Monomer and Polymer Embodiments, and Methods of Making and Using the Same. US Patent Appl. 63/221,718. PCT Application PCT/IB2022/052969. WO/2023/285883. | |
#85. | J. Wulff, R. Nazir, L. Bi and S. Musolino (2023) Diazirine-Based Epoxy Primers for the Preparation of Polymer Composite Materials. US Patent Appl. 63/254,669. WO/2023/060346. | |
#84. | B. Godwin, T. Olfatbakhsh, M. Mahbod, M. Takaffoli, A. Milani and J. E. Wulff (2023) A Single-Atom Upgrade to Polydicyclopentadiene. Macromolecules, 56, 1592–1600. (link) | |
#83. | F. Shatila, G. O. Tieman, S. F. Musolino, J. E. Wulff and H. L. Buckley (2023) Antimicrobial Photodynamic Inactivation of Planktonic and Biofilm Cells by Covalently Immobilized Porphyrin on Polyethylene Terephthalate Surface. International Biodeterioration & Biodegradation, 178, 105567. (link) | |
#82. | D. J. Blevins, R. Nazir, S. M. H. Dabri, M. Akbari, and J. E. Wulff (2022) The Effects of Cell Culture Conditions on Premature Hydrolysis of Traceless Ester-Linked Disulfide Linkers. Journal of Drug Delivery Science and Technology, 78, 103950. (link) | |
#81. | J. Wulff, P. Berrang, S. Musolino, R. Nazir, and L. Bi (2022) Aryl Ether Diazirines For Use in Polymer Crosslinking and Adhesion. US Patent Appl. 63/152,499 and 63/158,578. PCT Application CA2022/050293. WO/2022/187932. | |
#80. | J. E. Wulff, M. J. Baran, M. MacFarlane, R. Nazir, and M. McFarland (2022) Diazirine-Based Adhesives and Primers Facilitate Bonding to Low-Surface-Energy Plastics. Adhesives & Sealants Magazine, 99719. (link) | |
#79. | M.-H. Tran, I. Booth, B. G. daFonseca, P. Berrang, J. E. Wulff, and A. G. Brolo (2022) An Economical and Scalable Method to Synthesize Graphitic-Like Films. ACS Omega, 7, 43548–43558. (link) | |
#78. | S. Musolino, F. Shatila, G. M. O. Tieman, A. C. Masarsky, M. C. Thibodeau, J. E. Wulff, and H. L. Buckley (2022) Light-Induced Anti-Bacterial Effect Against Staphylococcus aureus of Porphyrin Covalently Bonded to a Polyethylene Terephthalate Surface. ACS Omega, 7, 29517–29525. (link) | |
#77. | S. Musolino, M. Mahbod, R. Nazir, L. Bi, H. A. Graham, A. S. Milani, and J. E. Wulff (2022) Electronically Optimized Diazirine-Based Polymer Crosslinkers. Polymer Chemistry, 13, 3833–3839. (link) | |
#76. | L. Silverman, G. Bhatti, J. E. Wulff and M. G. Moffitt (2022) Improvements in Drug Delivery Properties by Co-encapsulating Curcumin in SN-38-Loaded Anticancer Polymeric Nanoparticles. Molecular Pharmaceutics, 6, 1866–1881. (link) | |
#75. | X. Zhao, B. Khatir, L. Bi, J. E. Wulff and K. Golovin (2022) Crosslinking Inert Liquidlike Polydimethylsiloxane Brushes Using Bis-Diazirine Chemical Insertion for Enhanced Mechanical Durability. Chemical Engineering Journal, 442, 136017. (link) | |
#74. | R. Nazir, L. Bi, S. F. Musolino, O. H. Margoto, K. Çelebi, C. Mobuchon, M. Takaffoli, A. S. Milani, G. Falck, and J. E. Wulff (2022) Polyamine–Diazirine Conjugates for Use as Primers in UHMWPE–Epoxy Composite Materials. ACS Applied Polymer Materials, 4, 1728–1742. (link) | |
#73. | J. K. Sader, B. A. Molder and J. E. Wulff (2021) A Chan–Evans–Lam Approach to Trisubstituted Vinyl Ethers. Organic & Biomolecular Chemistry, 19, 9649–6018. (link) | |
#72. | M. L. Lepage, M. Takaffoli, C. Simhadri, R. Mandau, M. Parvinzadeh, R. Nazir, M. Mohseni, W. Li, C. Liu, L. Bi, G. Falck, P. Berrang, A. Milani, G. DiLabio and J. E. Wulff (2021) Influence of Topical Cross-Linking on Mechanical and Ballistic Performance of a Woven Ultra-High-Molecular-Weight Polyethylene Fabric Used in Soft Body Armor. ACS Applied Polymer Materials, 3, 6008–6018. (link) | |
#71. | H. Buckley, J. Wulff, P. Berrang, M. Lepage and S. Musolino (2021) Light-activated Pathogen-Killing Molecules and Uses Thereof. US Patent Appl. 62/987,599. PCT Application CA2021/050290. WO/2021/179064. | |
#70. | T. J. Cuthbert, S. Ennis, S. F. Musolino, H. L. Buckley, N. Niikura, J. E. Wulff and C. Menon (2021) Covalent Functionalization of Melt-Blown Polypropylene Filters with Diazirine–Photosensitizer Conjugates Producing Visible Light Driven Virus Inactivating Materials. Scientific Reports, 11, 19029. (link) | |
#69. | S. F. Musolino, Z. Pei, L. Bi, G. A. DiLabio and J. E. Wulff (2021) Structure–Function Relationships in Aryl Diazirines Reveal Optimal Design Features to Maximize C–H Insertion. Chemical Science, 12, 12138–12148. (link) | |
#68. | S. Kly, L. J. Andrew, E. G. Moloney, Y. Huang, J. E. Wulff and M. G. Moffitt (2021) A Hierarchical Self-Assembly Route to “Polyplex-in-Hydrophobic-Core” Micelles for Gene Delivery. Chemistry of Materials, 33, 6860–6875. (link) | |
#67. | C. Simhadri, L. Bi, M. L. Lepage, M. Takaffoli, Z. Pei, S. F. Musolino, A. S. Milani, G. A. DiLabio and J. E. Wulff (2021) Flexible Polyfluorinated Bis-Diazirines as Molecular Adhesives. Chemical Science, 12, 4147–4153. (link) | |
#66. | S. Musolino and J. E. Wulff (2021) Catalytic C–H Oxidation Enhances Polyethylene Bonding. Chem, 7, 7–9. (link) | |
#65. | T. Li and J. E. Wulff (2021) Copolymers of Functionalized and Nonfunctionalized Polydicyclopentadiene. ACS Applied Polymer Materials, 3, 110–115. (link) |
#64. | C. Lea, C. Simhadri, S. G. Bradbury, J. E. Wulff and C. P. Constabel (2021) Efficient Purification of the Diarylheptanoid Oregonin from Red Alder (Alnus rubra) Leaves and Bark Combining Aqueous Extraction, Spray Drying and Flash-Chromatography. Phytochemical Analysis, 32, 554–561. (link) | |
#63. | J. W. Saville, J. A. Ross, T. Trefz, C. Schatz, H. Matheson-Bird, B. Ralston, O. Granot, K. Schmid, R. Terry, N. Allan, J. E. Wulff and M. Olson (2020) Development and Field Validation of Lidocaine-Loaded Castration Bands for Bovine Pain Mitigation. Animals, 10, 2363. (link) | |
#62. | T. Li, H. Shumka, T. J. Cuthbert, C. Liu and J. E. Wulff (2020) Harnessing the Surface Chemistry of Methyl Ester Functionalized Polydicyclopentadiene and Exploring Surface Bioactivity. Materials Advances, 1, 1753–1762. (link) | |
#61. | C. Fellenberg, O. Corea, L.-H. Yang, F. Archinuk, E.-M. Piirtola, H. Gordon, M. Reichelt, W. Brandt, J. Wulff, J. Ehlting, and C. P. Constabel (2020) Discovery of Salicyl Benzoate UDP-glycotransferase, a Central Enzyme in Poplar Salicinoid Phenolic Glycoside Biosynthesis. The Plant Journal, 102, 99–115. (link) | |
#60. | M. L. Lepage, C. Simhadri, C. Liu, M. Takaffoli, L. Bi, B. Crawford, A. S. Milani, and J. E. Wulff (2019) A Broadly Applicable Cross-Linker for Aliphatic Polymers Containing C–H Bonds. Science, 366, 875–878. (link) | |
#59. | J. E. Wulff, P. G. Berrang, M. L. Lepage, and C. Simhadri (2019) Diazirine-based Molecules and Uses Thereof. US Patent Appl. 62/839,062. PCT Application CA2020/050278. WO/2020/215144. | |
#58. | T. J. Cuthbert, T. Li, and J. E. Wulff (2019) Production and Dynamic Mechanical Analysis of Macro-Scale Functionalized Polydicyclopentadiene Objects Facilitated by Rational Synthesis and Reaction Injection Molding. ACS Applied Polymer Materials, 1, 2460–2471. (link) | |
#57. | J. K. Sader and J. E. Wulff (2019) Reinvestigation of a Robotically Revealed Reaction. Nature, 570, E54–E59. (link) | |
#56. | D. J. Blevins, R. Hanley, T. Bolduc, D. A. Powell, M. Gignac, K. Walker, M. D. Carr, F. Hof and J. E. Wulff (2019) In Vitro Assessment of Putative PD-1/PD-L1 Inhibitors: Suggestions of an Alternative Mode of Action. ACS Medicinal Chemistry Letters, 10, 1187–1192. (link) | |
#55. | C. Simhadri, K. D. Daze, S. F. Douglas, N. Milosevich, L. Monjas, A. Dev, T. M. Brown, A. K. H. Hirsch, J. E. Wulff and F. Hof (2019) Rational Adaptation of L3MBTL1 Inhibitors to Create Small-Molecule Cbx7 Antagonists. ChemMedChem, 14, 1444–1456. (link) | |
#54. | N. Dao, J. K. Sader, A. G. Oliver and J. E. Wulff (2019) Prying Open a Thiele Cage Through an Unprecedented Extended Pinacol Reaction. Chemical Communications, 55, 1600–1603. (link) | |
#53. | Y. Cao, L. Silverman, C. Lu, R. Hof, J. E. Wulff and M. Moffitt (2019) Microfluidic Manufacturing of SN-38-Loaded Polymer Nanoparticles with Shear Processing Control of Drug Delivery Properties. Molecular Pharmaceuticals, 16, 96–107. (link) | |
#52. | D. Jensen, Y. Cao, C. Lu, J. E. Wulff and M. Moffitt (2019) Microfluidic Encapsulation of SN-38 in Block Copolymer Nanoparticles: Effect of Hydrophobic Block Composition on Loading and Release Properties. Canadian Journal of Chemistry, 97, 337–343. (link) | |
#51. | R. Chen, J. E. Wulff and M. Moffitt (2018) Microfluidic Processing Approach to Controlling Drug Delivery Properties of Curcumin-Loaded Block Copolymer Nanoparticles. Molecular Pharmaceuticals, 15,4517–4528. (link) | |
#50. | T. J. Cuthbert, T. Li, A. W. H. Speed and J. E. Wulff (2018) Structure of the Thermally Induced Cross-Link in C-Linked Methyl Ester Functionalized Polydicyclopentadiene. Macromolecules, 51, 2038–2047. (link) | |
#49. | C. H. A. Un and J. E. Wulff (2018) 3-Sulfolene [First Update]. Electronic Encyclopedia of Reagents for Organic Synthesis, DOI: 10.1002/047084289X.rs130.pub2. (link) | |
#48. | J. Chen, L. Lu and J. E. Wulff (2017) Radical Stabilization Logic as a Predictive Tool for Novel and Reported Non-Canonical Thiele’s Acid Analogues. SynLett, 28, 2777–2782. (link) | |
#47. | Z. Xu, C. Lu, C. Lindenberger, Y. Cao, J. E. Wulff and M. G. Moffitt (2017) Synthesis, Self-Assembly, and Drug Delivery Characteristics of Poly(methyl caprolactone-co-caprolactone)-b-poly(ethylene oxide) Copolymers with Variable Compositions of Hydrophobic Blocks: Combining Chemistry and Microfluidic Processing for Polymeric Nanomedicines. ACS Omega, 2, 5289–5303. (link) | |
#46. | A. Bains, Y. Cao, S. Kly, J. E. Wulff and M. G. Moffitt (2017) Controlling Structure and Function of Polymeric Drug Delivery Nanoparticles Using Microfluidics. Molecular Pharmaceutics, 14, 2595–2606. (link) | |
#45. | L. E. B. Bettio, J. Gil-Mohapel, A. R. Patten, N. F. O'Rourke, R. P. Hanley, K. Gopalakrishnan, J. E. Wulff and B. R. Christie (2017) Effects of Isx-9 and Stress on Adult Hippocampal Neurogenesis: Experimental Considerations and Future Perspectives. Neurogenesis, 4, e1317692. (link) | |
#44. | J. Chen, X. Sun, A. G. Oliver and J. E. Wulff (2017) Resolution of Thiele's Acid. Canadian Journal of Chemistry, 95, 234–238. (link) | |
#43. | J. Chen and J. E. Wulff (2016) Revisiting the Mechanistic Origins of Thiele's Ester Dimerization: Probing the Reliability of Predictive Methods for Cycloadditions. Organic & Biomolecular Chemistry, 14, 10170–10174. (link) | |
#42. | J. Chen, F. P. Burns, M. G. Moffitt and J. E. Wulff (2016) Thermally Crosslinked Functionalized Polydicyclopentadiene with a Hight Tg and Tunable Surface Energy. ACS Omega, 1, 532–540. (link) | |
#41. | C. Simhadri, M. C. Gignac, C. J. Anderson, N. Milosevich, A. Dheri, N. Prashar, R. T. Flemmer, A. Dev, T. G. Henderson, S. F. Douglas, J. E. Wulff and F. Hof (2016) Structure–Activity Relationships of Cbx7 Inhibitors, Including Selectivity Studies against Other Cbx Proteins. ACS Omega, 1, 541–551. (link) | |
#40. | L. E. Bettio, A. R. Patten, J. Gil-Mohapel, N. F. O'Rourke, R. P. Hanley, S. Kennedy, K. Gopalakrishnan, A. L. Rodrigues, J. Wulff and B. R. Christie (2016) The Small Synthetic Molecule, ISX-9, Can Potentiate Cell Proliferation and Differentiation in the Rat Dentate Gyrus. Neuroscience, 332, 212–222. (link) | |
#39. | J. E. Wulff, J. Chen, T. G. Cuthbert, T. Li, C. Liu, M. G. Moffitt and F. Burns (2016) Functionalized Polydicyclopentadiene Polymer. US Patent Appl. 62/297,567, 62/347,446, and 15/999,209. Allowed May 13, 2019. | |
#38. | A. Bains, J. E. Wulff and M. G. Moffitt (2016) Microfluidic Synthesis of Dye-Loaded Polycaprolactone-block-poly(ethylene oxide) Nanoparticles: Insights into Flow-Directed Loading and In Vitro Release for Drug Delivery. Journal of Colloids and Interface Science, 475, 136–148. (link) | |
#37. | R. P. Hanley, S. Horvath, J. An, F. Hof and J. E. Wulff (2016) Salicylates are Interference Compounds in TR-FRET Assays. Bioorganic & Medicinal Chemistry Letters, 26, 973–977. (link) | |
#36. | N. Milosevich, M. C. Gignac, J. McFarlane, C. Simhadri, S. Horvath, K. D. Daze, C. S. Croft, A. Dheri, T. T. H. Quon, S. F. Douglas, J. E. Wulff, I. Paci and F. Hof (2016) Selective Inhibition of CBX6: A Methyllysine Reader Protein in the Polycomb Family. ACS Medicinal Chemistry Letters, 7, 139–144. (link) | |
#35. | M. G. Brant and J. E. Wulff (2016) Substituted 3-Sulfolenes: Synthesis and Applications. Synthesis, 48, 1–17. (link) | |
#34. | J. Chen, B. Kilpatrick, A. G. Oliver and J. E. Wulff (2015) Expansion of Thiele's Acid Chemistry in Pursuit of a Suite of Conformationally Constrained Scaffolds. Journal of Organic Chemistry, 80, 8979–8989. (link) | |
#33. | M. G. Brant, J. Friedmann, C. Bohlkin, A. G. Oliver and J. E. Wulff (2015) Tandem reactions of substituted 3-sulfolenes with bis-vinyl ketones leading to highly functionalized bicyclic and tricyclic frameworks. Organic and Biomolecular Chemistry, 13, 4581–4588. (link) | |
#32. | J. A. Davy, B. Moreau, A. G. Oliver and J. E. Wulff (2015) A symmetry-driven approach to the putative spiroketal core of the didemnaketals. Tetrahedron, 71, 2643–2657. (link) | |
#31. | J. Wulff (2015) Young career focus article. Synform, A62–A63. (link) | |
#30. | R. Stoddard, J. Luo, N. van der Wal, N. F. O’Rourke, J. E. Wulff and S. McIndoe (2014) A multi-pronged mechanistic study of the conjugate addition of alcohols to alkynic esters. New Journal of Chemistry, 38, 5382–5390. (link) | |
#29. | M. R. Richards, M. G. Brant, M. Boulanger, C. W. Cairo and J. E. Wulff (2014) Conformational Analysis of Peramivir Reveals Critical Differences Between Free and Enzyme-Bound States. MedChemComm, 5, 1483–1488. (link) | |
#28. | C. Simhadri, K. D. Daze, S. F. Douglas, T. T. H. Quon, M. Gicnac, A. Dev, F. Peng, M. Heller, M. J. Boulanger, J. E. Wulff and F. Hof (2014) Chromodomain antagonists that target the polycomb-group methyllysine reader protein Chromobox homolog 7 (CBX7). Journal of Medicinal Chemistry, 57, 2874–2883. (link) | |
#27. | N. F. O’Rourke and J. E. Wulff (2014) Investigation of Quantitative Structure-Reactivity Relationships in the Aliphatic Claisen Rearrangement of Bis-Vinyl Ethers Reveals a Dipolar, Dissociative Mechanism. Organic & Biomolecular Chemistry, 12, 1292–1308. (link) | |
#26. | S. Tabet, S. F. Douglas, K. D. Daze, G. A. Garnett, K. J. Allen, E. M. Abrioux, T. T. Quon, J. E. Wulff and F. Hof (2013) Synthetic Trimethyllysine Receptors That Bind Histone 3, Trimethyllysine 27 (H3K27me3) and Disrupt its Interaction with the Epigenetic Reader Protein CBX7. Bioorganic and Medicinal Chemistry, 21, 7004–7010. (link) | |
#25. | S. S. Y. Wong, M. G. Brant, C. Barr, A. G. Oliver and J. E. Wulff (2013) Dipolar Addition to Cyclic Vinyl Sulfones Leading to Dual Conformation Tricycles. Beilstein Journal of Organic Chemistry, 9,1419–1425. (link) | |
#24. | M. G. Brant and J. E. Wulff (2012) A Rigid Bicyclic Platform for the Generation of Conformationally Locked Neuraminidase Inhibitors. Organic Letters, 14,5876–5879. (link) | |
#23. | N. F. O'Rourke, K. A. Davies and J. E. Wulff (2012) Mechanistic Studies on an Apparent 6-endo / 5-exo Radical Cascade Across Bis-Vinyl Ether Substrates Reveal a 5-exo / 3-exo / retro-3-exo Cascade. Journal of Organic Chemistry, 77, 8634–8647. (link) | |
#22. | J. Bains, J. E. Wulff and M. J. Boulanger (2012) Investigating Terephthalate Biodegradation: Structural Characterization of a Putative Decarboxylating Cis-Dihydrodiol Dehydrogenase. Journal of Molecular Biology, 423,284–293. (link) | |
#21. | J. E. Wulff, M. G. Brant, and J. W. Mason (2012, 2013) Bicyclic Compounds as Therapeutic Agents for the Treatment of Cancer. Provisional Filing 61/683,586; US National Filing 13/956,055. | |
#20. | J. A. Davy, J. M. Mason, B. Moreau and J. E. Wulff (2012) Xanthates as Synthetic Equivalents of Oxyacyl Radicals: Access to Lactones under Tin-Free Conditions. Journal of Organic Chemistry, 77,6332–6339. (link) | |
#19. | J. A. Davy, B. Moreau and J. E. Wulff (2012) Tandem Dihydroxylation / Hemiketalization / Conjugate Addition Leading to a Singly Anomeric Spiroketal. Syntheis Special Issue on Tandem Reactions in Organic Chemistry, 44, 1854–1862. (link) | |
#18. | C. M. Bromba, J. W. Mason, M. G. Brant, T. Chan, M. Lunke, M. Petric, M. J. Boulanger and J. E. Wulff (2011) The De-guanidinylated Derivative of Peramivir Remains a Potent Inhibitor of Influenza Neuraminidase. Bioorganic and Medicinal Chemistry Letters, 21, 7137–7141. (link) | |
#17. | K. A. Davies and J. E. Wulff (2011) Marrying Iterative Synthesis to Cascading Radical Cyclization: 6-endo / 5-exo Radical Cascade Across Bis-Vinyl Ethers. Organic Letters, 13, 5552–5555. (link) | |
#16. | A. Hinther, C. M. Bromba, J. E. Wulff and C. C. Helbing (2011) Effects of Triclocarban, Triclosan, and Methyl Triclosan on Thyroid Hormone Action and Stress in Frog and Mammalian Culture Systems. Environmental Science and Technology, 45, 5395–5402. (link) | |
#15. | K. A. Davies, K. G. M. Kou and J. E. Wulff (2011) Oxygen-Containing Analogues of Juvenile Hormone III. Tetrahedron Letters, 52, 2302–2305. (link) | |
#14. | M. G. Brant, C. M. Bromba and J. E. Wulff (2010) Tandem Vinylogous 1,2-Addition/Anionic Oxy-Cope Reaction Leading from Butadiene Sulfone to an Orthogonally Functionalized Bicycle. Journal of Organic Chemistry, 75, 6312–6315. (link) | |
#13. | J. E. Wulff, M. G. Brant, C. M. Bromba, J. W. Mason and M. J. Boulanger (2010, 2011, 2012) Synthesis of Bicyclic Compounds and Method for their Use as Therapeutic Agents. US Patent Appl. 61/304,738; PCT Application PCT/CA2011/000174; WO 2011097717; US Patent Appl. 61/591,630; US National Filing 13/586,687. | |
#12. | K. A. Davies, R. C. Abel and J. E. Wulff (2009) Operationally Simple Copper-Promoted Coupling of Terminal Alkynes with Benzyl Halides. Journal of Organic Chemistry, 74, 3997–4000. (link) | |
#11. | J. E. Wulff, R. Siegrist and A. G. Myers (2007) The Natural Product Avrainvillamide Binds to the Oncoprotein Nucleophosmin. Journal of the American Chemical Society, 129, 14444–14451. (link) | |
#10. | A. G. Myers, J. E. Wulff, R. Siegrist and C. F. Nising (2007) Targeting the Oncoprotein Nucleophosmin. WO 2009020768; US 20110105515; US 2007-954393P; US 2008-50700P; WO 2008-US70984. | |
#9. | J. E. Wulff, S. B. Herzon, R. Siegrist and A. G. Myers (2007) Evidence for the Rapid Conversion of Stephacidin B into the Electrophilic Monomer Avrainvillamide in Cell Culture. Journal of the American Chemical Society, 129,4898–4899. (link) | |
#8. | J. M. Sorbetti, K. N. Clary, D. A. Rankic, J. E. Wulff, M. Parvez and T. G. Back (2007) Aza-Morita-Baylis-Hillman Reactions and Cyclizations of Conjugated Dienes Activated by Sulfone, Ester, and Keto Groups. Journal of Organic Chemistry, 72, 3326–3331. (link) | |
#7. | A. G. Myers, S. B. Herzon, J. E. Wulff, R. Siegrist, J. Svenda and M. A. Zajac (2006) Synthesis of Avrainvillamide, Stephacidin B, and Analogues Thereof. WO 2006102097; WO 2006102097; AU 2006227379; AU 2006227379; CA 2601135; EP 1863800; JP 2008537544; IN 2007KN03743; CN 101189229; US 20090143581; US 7902196; US 2005-662647P; WO 2006-US9749; US 2008-908901. | |
#6. | T. G. Back, D. A. Rankic, J. M. Sorbetti and J. E. Wulff (2005) Morita-Baylis-Hillman Reaction and Cyclization of 1-(p-Toluenesulfonyl)-1,3-butadiene with Aldimines. Organic Letters, 7, 2377–2379. (link) | |
#5. | T. G. Back and J. E. Wulff (2004) A Stereodivergent Synthesis of Virantmycin by an Enzyme-Mediated Diester Desymmetrization and a Highly Hindered Aryl Amination. Angewandte Chemie International Edition, English, 43, 6493–6496. (link) | |
#4. | T. G. Back, A. Pandyra and J. E. Wulff. (2003) Regiochemical Switching in Diels-Alder Cycloadditions by Change in Oxidation State of Removable Diene Sulfur Substituents. Synthesis of Carbazoles by Sequential Heteroannulation and Diels-Alder Cycloaddition. Journal of Organic Chemistry, 68, 3299–3302. (link) | |
#3. | T. G. Back, M. Parvez and J. E. Wulff. (2003) Conjugate Additions of o-Iodoanilines and Methyl Anthranilates to Acetylenic Sulfones. A New Route to Quinolones Including First Syntheses of Two Alkaloids from the Medicinal Herb Ruta Chalepensis. Journal of Organic Chemistry, 68, 2223–2233. (link) | |
#2. | T. G. Back and J. E. Wulff. (2002) Se-Phenyl p-tolueneselenosulfonate. Electronic Encyclopedia of Reagents for Organic Synthesis. Wiley Interscience. Ed. L. Paquette. (link) | |
#1. | T. G. Back and J. E. Wulff. (2002) First Synthesis of Two Quinoline Alkaloids from the Medicinal Herb Ruta Chalepensis via Cyclization of an o-Iodoaniline with an Acetylenic Sulfone. Chemical Communications, 1710–1711. (link) | |