Publications

38. Subrata Jana, Amanda L. Whiting, Anita Hazra, Saikat Sen, Shyamaprosad Goswami, Goverdhan Mehta, Hoong-Kun Fun, and Fraser Hof* Anion recognition by a novel preorganized binding motif: amide-functionalized quinoliniums characterized in the solid state and in solution Supramol. Chem. 2012, in press.

37. Kevin D. Daze, Manuel C.F. Ma, Florent Pineux, and Fraser Hof* Synthesis of new trisulfonated calix[4]arenes functionalized at the upper rim, and their complexation with the trimethyllysine epigenetic mark Org. Lett. 2012, in press.

36. Xing Wang and Fraser Hof* (How) does 1,3,5-triethylbenzene scaffolding work? Analyzing the abilities of 1,3,5-triethylbenzene- and 1,3,5-trimethylbenzene-based scaffolds to preorganize the binding elements of supramolecular hosts and to improve binding of targets. Beil. J. Org. Chem. 2012, 8, 1–10. web

35. Rebecca J.M. Courtemanche, Thomas Pinter, and Fraser Hof* Just add tetrazole: 5-(2-pyrrolo)tetrazoles are potent anion recognition elements Chem. Commun. 2011, 47, 12688–12690. web supp info

34. Thomas Pinter, Subrata Jana, Rebecca J.M. Courtemanche, and Fraser Hof* The recognition properties of carboxylic acid bioisosteres: anion binding by tetrazoles, aryl sulfonamides and acyl sulfonamides on a calix[4]arene scaffold, J. Org. Chem., 2011, 76, 3733–3741. web supp info

33. Jennifer Pape, Keri McQuinn, Fraser Hof, and J. Scott McIndoe* Blurring the line between solution and the gas phase: evaporation of water from hypersolvated lanthanide trications provides insights into solution acidity, New. J. Chem., 2011, 35, 1582–1587. web journal cover (pdf)

32. M. Adil Khan, Joel Moktar, Patrick Mott, Mary Vu, Aaron H. McKie, Thomas Pinter, Fraser Hof,* and Russell Bishop* Inscribing the perimeter of the PagP hydrocarbon ruler by site-specific chemical alkylation, Biochemistry, 2010, 49, 9046–9057. web

31. Cory S. Beshara and Fraser Hof* Modular incorporation of 1-benzyltryptophan into dipeptide hosts that bind acetylcholine in pure water, Can. J. Chem., 2010, 88, 1009–1016 (cover of Oct. 2010 issue). web supp info

30. Cory S. Beshara, Catherine E. Jones, Kevin D. Daze, Brandin J. Lilgert, and Fraser Hof* A simple calixarene recognizes post-translationally methylated lysine,  ChemBioChem, 2010, 11, 63–66. web supp info

29. Nathan R. West, Benjamin Farnell, Jill I. Murray, Fraser Hof,* Peter H. Watson,* and Martin J. Boulanger,* Structural and functional characterization of a triple mutant form of S100A7 defective for Jab1 binding Protein Sci., 2009, 18, 2615–2623. web

28. Rafaél León, Jill I. Murray, Gina Cragg, Benjamin Farnell, Nathan R. West, Tamara Pace, Peter H. Watson, Cornelia Bohne,* Martin J. Boulanger,* and Fraser Hof* Identification and characterization of binding sites on S100A7, a participant in cancer and inflammation pathways Biochemistry, 2009, 48, 10591–10600. web

27. Amanda L. Whiting, Nicole M. Neufeld, Fraser Hof* A tryptophan-analog host whose interactions with ammonium ions in water are dominated by the hydrophobic effect Tet. Lett., 2009, 50, 7035–7037. web supp info

26. Keri McQuinn, Fraser Hof,* J.S. McIndoe,* X. Chen, G. Wu, A.J.  Stace* Evidence of asymmetric cation solvation from the instability of [Pb(H2O)n]2+ complexes Chem. Commun. 2009, 4088–4091. web supp info

25. Martina Zürcher, Fraser Hof, Luzi Barandun, Andri Schütz, W. Bernd Schweizer, Solange Meyer, Daniel Bur, François Diederich Synthesis of exo-3-amino-7-azabicyclo[2.2.1]heptanes as a class of malarial aspartic protease inhibitors: exploration of two binding pockets Eur. J. Org. Chem. 2009, 1707–1719. web
 
24. Keri McQuinn, Fraser Hof,* and J. Scott McIndoe* Collision-induced dissociation of large protonated water clusters Int. J. Mass Spectrom. 2009, 279, 32–36. web supp info

23. Aaron H. McKie, Sayuri Friedland, and Fraser Hof* Tetrazoles are potent anion binding elements that emulate the disfavoured anti conformation of carboxylic acids Org. Lett. 2008 10(20), 4653–4655. web supp info

22. Keri McQuinn, J. Scott McIndoe*, and Fraser Hof* Insights into the post-translational methylation of arginine from studies of guanidinium-water nanodroplets Chem. Eur. J. 2008, 14(21), 6483–6489. web supp info

21. Xing Wang, Olga V. Sarycheva, Bryan D. Koivisto, Aaron H. McKie, and Fraser Hof* A terphenyl scaffold for pi-stacked guanidinium recognition elements Org. Lett. 2008, 10(2), 297–300. web supp info

20. Keri McQuinn, Fraser Hof*, and J. Scott McIndoe* Direct observation of ion evaporation from a triply charged nanodroplet Chem. Commun. 2007, 4099–4101. web supp. info.

19. Devin J. Mahnke, R. McDonald, and Fraser Hof* A shape-dependent hydrophobic effect for tetrazoles Chem. Commun. 2007, 3738–3740. web supp. info.

18. Fraser Hof, Andri Schütz, Christoph Fäh, Solange Meyer, Daniel Bur, Jun Liu, Daniel E. Goldberg, and François Diederich Starving the Malaria Parasite: A New Class of Inhibitors Active Against the Aspartic Proteases Plasmepsins I, II, and IV Angew. Chem. Int. Ed. 2006, 45(13), 2138–2141. web

17. Orion B. Berryman, Fraser Hof, Michael J. Hynes and Darren W. Johnson Anion–pi interaction augments halide binding in solution Chem. Commun. 2006, 506–508. web

16. Fraser Hof, Sergey Sergeyev, Mikhail Shair, Denise M. Scofield, Felix Fischer, and François Diederich Preparation of Tröger Base Derivatives Using Cross-Coupling Methodologies Helv. Chim. Acta 2005, 88(8), 2333–2344.  web

15.  Fraser Hof, Denise M. Scofield, W. Bernd Schweizer, and François Diederich A Weak Attractive Interaction Between Organic Fluorine and an Amide Angew. Chem. Int. Ed. 2004, 43(38), 5056–5059.  web

14.  Fraser Hof and François Diederich Medicinal Chemistry in Academia: Molecular Recognition with Biological Receptors Chem. Commun. 2004, (5), 484-487.  web

13.  Shannon M. Biros, Elke C. Ullrich, Fraser Hof, Laurent Trembleau, and Julius Rebek, Jr. Kinetically Stable Complexes in Water: The Role of Hydration and Hydrophobicity J. Am. Chem. Soc. 2004, 126(9), 2870-2874.  web

12. Darren W. Johnson, Fraser Hof, Liam C. Palmer, Tomás Martín, Ulrike Obst, and Julius Rebek, Jr. Glycoluril Ribbons Tethered by Complementary Hydrogen Bonds Chem. Commun. 2003, 14, 1638-1639.  web 

11. Fraser Hof, Laurent Trembleau, Elke Christine Ullrich, and Julius Rebek, Jr. Acetylcholine Recognition by a Deep, Biomimetic Pocket Angew. Chem. Int. Ed. 2003, 42(27), 3150-3153.  web 

10. Darren W. Johnson, Fraser Hof, Peter M. Iovine, Colin Nuckolls, and Julius Rebek, Jr. Solid State and Solution Studies of a Tetrameric Hydrogen-Bonded Capsule and its Guests Angew. Chem. Int. Ed. 2002, 41(20), 3793-3796.  web

9. Darren W. Johnson, Liam C. Palmer, Fraser Hof, Peter M. Iovine, and Julius Rebek, Jr. New Supramolecular Organization for Glycoluril: Chiral Hydrogen-Bonded Ribbons Chem. Commun. 2002, 2228-2229.  web

8. Fraser Hof, Stephen L. Craig, Colin Nuckolls, and Julius Rebek, Jr. Molecular Encapsulation Angew. Chem. Int. Ed. 2002, 41(9), 1488-1508. (selected for cover of 2002 issue #9) web

7. Fraser Hof and Julius Rebek, Jr. Molecules-Within-Molecules: Molecular Recognition Through Self-Assembly Proc. Nat. Acad. Sci. U.S.A. 2002, 99(8), 4775-4777. web

6. Fraser Hof, Peter M. Iovine, Darren W. Johnson, and Julius Rebek, Jr. Highly Selective Synthesis of Heterosubstituted Aromatic Sulfamides Org. Lett. 2001, 3 (26), 4247-4249.  web

5. Fraser Hof, Liam C. Palmer, and Julius Rebek, Jr. Synthesis and Self-Assembly of the "Tennis Ball" Dimer and Subsequent Encapsulation of Methane: An Advanced Organic Chemistry Laboratory Experiment J. Chem. Ed. 2001, 78, 1519-1524. pdf

4. Fraser Hof, Colin Nuckolls, Stephen L. Craig, Tomas Martín, and Julius Rebek, Jr. Emergent Conformational Preferences of a Self-Assembling Small Molecule: Structure and Dynamics in a Tetrameric Capsule, J. Am. Chem. Soc. 2000, 122 (17), 10991-10996. web

3. Fraser Hof, Colin Nuckolls, and Julius Rebek, Jr. Diversity and Selection in Self-Assembled Tetrameric Capsules, J. Am. Chem. Soc. 2000, 122 (17), 4251-4252. web

2. Colin Nuckolls, Fraser Hof, Tomas Martín, and Julius Rebek, Jr. Chiral Microenvironments in Self-Assembled Capsules, J. Am. Chem. Soc. 1999, 121 (44), 10281-10285. web

1. Marcelo M. M. Pelisson, Gil Valdo José da Silva, Derrick L. J. Clive, Don M. Coltart, and Fraser A. Hof Studies on the Preparation of 3,4-Disubstituted 2-Methoxypyridines, J. Het. Chem. 1999, 36, 653-658.